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Timing considerations for giving Shingrix

For patients who previously had herpes zoster

There is no specific amount of time you need to wait before administering Shingrix to patients who have had herpes zoster.

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However, you should not give Shingrix to patients who are experiencing an acute episode of herpes zoster.

For patients who previously received Zostavax

Zostavax is no longer available for use in the United States, as of November 18, 2020.

Consider the patient’s age and when they received Zostavax to determine when to vaccinate with Shingrix. Studies examined the safety of Shingrix vaccination 5 or more years after Zostavax vaccination. Shorter intervals were not studied, but there are no theoretical or data concerns to indicate that Shingrix would be less safe or effective if administered less than 5 years after a patient received Zostavax.

You may consider an interval shorter than 5 years between Zostavax and Shingrix based on the age at which the patient received Zostavax.

Differences in efficacy between Shingrix and Zostavax a

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